computer simulator Search Results


fluent computational fluid dynamics software  (ANSYS inc)
90
ANSYS inc fluent computational fluid dynamics software
Fluent Computational Fluid Dynamics Software, supplied by ANSYS inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fluent computational fluid dynamics software/product/ANSYS inc
Average 90 stars, based on 1 article reviews
fluent computational fluid dynamics software - by Bioz Stars, 2026-04
90/100 stars
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human head computer simulations  (ANSYS inc)
90
ANSYS inc human head computer simulations
Human Head Computer Simulations, supplied by ANSYS inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human head computer simulations/product/ANSYS inc
Average 90 stars, based on 1 article reviews
human head computer simulations - by Bioz Stars, 2026-04
90/100 stars
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computer-based simulation  (Simcyp)
90
Simcyp computer-based simulation
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Computer Based Simulation, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/computer-based simulation/product/Simcyp
Average 90 stars, based on 1 article reviews
computer-based simulation - by Bioz Stars, 2026-04
90/100 stars
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computational fluid dynamics simulation  (Aerodyne Research Inc)
90
Aerodyne Research Inc computational fluid dynamics simulation
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Computational Fluid Dynamics Simulation, supplied by Aerodyne Research Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/computational fluid dynamics simulation/product/Aerodyne Research Inc
Average 90 stars, based on 1 article reviews
computational fluid dynamics simulation - by Bioz Stars, 2026-04
90/100 stars
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computer-aided design simulation  (Silvaco Inc)
90
Silvaco Inc computer-aided design simulation
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Computer Aided Design Simulation, supplied by Silvaco Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/computer-aided design simulation/product/Silvaco Inc
Average 90 stars, based on 1 article reviews
computer-aided design simulation - by Bioz Stars, 2026-04
90/100 stars
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computed tomography simulator somatom sensation opentm  (Siemens Healthineers)
90
Siemens Healthineers computed tomography simulator somatom sensation opentm
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Computed Tomography Simulator Somatom Sensation Opentm, supplied by Siemens Healthineers, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/computed tomography simulator somatom sensation opentm/product/Siemens Healthineers
Average 90 stars, based on 1 article reviews
computed tomography simulator somatom sensation opentm - by Bioz Stars, 2026-04
90/100 stars
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digital-computer simulation  (Tracor Inc)
90
Tracor Inc digital-computer simulation
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Digital Computer Simulation, supplied by Tracor Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/digital-computer simulation/product/Tracor Inc
Average 90 stars, based on 1 article reviews
digital-computer simulation - by Bioz Stars, 2026-04
90/100 stars
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docking simulation software  (Chemical Computing Group)
90
Chemical Computing Group docking simulation software
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Docking Simulation Software, supplied by Chemical Computing Group, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/docking simulation software/product/Chemical Computing Group
Average 90 stars, based on 1 article reviews
docking simulation software - by Bioz Stars, 2026-04
90/100 stars
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computational fluid dynamics simulation package comsol multiphysics v6.2  (COMSOL Inc)
90
COMSOL Inc computational fluid dynamics simulation package comsol multiphysics v6.2
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Computational Fluid Dynamics Simulation Package Comsol Multiphysics V6.2, supplied by COMSOL Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/computational fluid dynamics simulation package comsol multiphysics v6.2/product/COMSOL Inc
Average 90 stars, based on 1 article reviews
computational fluid dynamics simulation package comsol multiphysics v6.2 - by Bioz Stars, 2026-04
90/100 stars
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computed tomography simulator philips medical systems  (Philips Healthcare)
90
Philips Healthcare computed tomography simulator philips medical systems
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Computed Tomography Simulator Philips Medical Systems, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/computed tomography simulator philips medical systems/product/Philips Healthcare
Average 90 stars, based on 1 article reviews
computed tomography simulator philips medical systems - by Bioz Stars, 2026-04
90/100 stars
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fluid analysis software star-cd  (Adapco Inc)
90
Adapco Inc fluid analysis software star-cd
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Fluid Analysis Software Star Cd, supplied by Adapco Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fluid analysis software star-cd/product/Adapco Inc
Average 90 stars, based on 1 article reviews
fluid analysis software star-cd - by Bioz Stars, 2026-04
90/100 stars
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computer simulation software cerius  (Accelrys)
90
Accelrys computer simulation software cerius
Time-course of <t>erlotinib</t> depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.
Computer Simulation Software Cerius, supplied by Accelrys, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/computer simulation software cerius/product/Accelrys
Average 90 stars, based on 1 article reviews
computer simulation software cerius - by Bioz Stars, 2026-04
90/100 stars
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Image Search Results


Time-course of erlotinib depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Time-course of erlotinib depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), ritonavir (●) or ketoconazole (□). Data are representative of three to six individual experiments each performed in duplicate. Error bars represent standard deviation.

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Standard Deviation

Area under the concentration-time curve for erlotinib depletion and desmethyl erlotinib formation in primary cultures of human hepatocytes treated with vehicle (DMSO), ritonavir, or ketoconazole and incubated with erlotinib (5 μ M)

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Area under the concentration-time curve for erlotinib depletion and desmethyl erlotinib formation in primary cultures of human hepatocytes treated with vehicle (DMSO), ritonavir, or ketoconazole and incubated with erlotinib (5 μ M)

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Concentration Assay, Incubation

Half-life ( t 1/2 ), % erlotinib metabolized after 48 hours, M/P to AUC ratio, T max of desmethyl erlotinib, and apparent intrinsic clearance (CL int, app ) of erlotinib in primary cultures of human hepatocytes treated with vehicle (DMSO), ritonavir, or ketoconazole and incubated with erlotinib (5 μ M)

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Half-life ( t 1/2 ), % erlotinib metabolized after 48 hours, M/P to AUC ratio, T max of desmethyl erlotinib, and apparent intrinsic clearance (CL int, app ) of erlotinib in primary cultures of human hepatocytes treated with vehicle (DMSO), ritonavir, or ketoconazole and incubated with erlotinib (5 μ M)

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Incubation

Time-course of erlotinib depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), efavirenz (●), or rifampin (□). Data are representative of three individual experiments each performed in duplicate. Error bars represent standard deviation.

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Time-course of erlotinib depletion (A) and formation of desmethyl erlotinib (B) in primary cultures of human hepatocytes treated with DMSO (○), efavirenz (●), or rifampin (□). Data are representative of three individual experiments each performed in duplicate. Error bars represent standard deviation.

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Standard Deviation

Area under the concentration-time curve for erlotinib depletion and desmethyl erlotinib formation in primary cultures of human hepatocytes treated with vehicle (DMSO), efavirenz, or rifampin and incubated with erlotinib (5 μ M)

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Area under the concentration-time curve for erlotinib depletion and desmethyl erlotinib formation in primary cultures of human hepatocytes treated with vehicle (DMSO), efavirenz, or rifampin and incubated with erlotinib (5 μ M)

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Concentration Assay, Incubation

Half-life ( t 1/2 ), % erlotinib metabolized after 8 and 24 hours, M/P to AUC ratio, T max of desmethyl erlotinib, and apparent intrinsic clearance (CL int, app ) of erlotinib in primary cultures of human hepatocytes treated with vehicle (DMSO), efavirenz, or rifampin and incubated with erlotinib (5 μ M)

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Half-life ( t 1/2 ), % erlotinib metabolized after 8 and 24 hours, M/P to AUC ratio, T max of desmethyl erlotinib, and apparent intrinsic clearance (CL int, app ) of erlotinib in primary cultures of human hepatocytes treated with vehicle (DMSO), efavirenz, or rifampin and incubated with erlotinib (5 μ M)

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Incubation

Predicted human hepatic or oral clearance (CLhep or CLoral) of erlotinib from primary cultures of human hepatocytes treated with DMSO, ritonavir, or ketoconazole. *P < 0.05 versus DMSO; nonparametric Friedman analysis of variance followed by Dunn’s multiple comparison test.

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Predicted human hepatic or oral clearance (CLhep or CLoral) of erlotinib from primary cultures of human hepatocytes treated with DMSO, ritonavir, or ketoconazole. *P < 0.05 versus DMSO; nonparametric Friedman analysis of variance followed by Dunn’s multiple comparison test.

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Comparison

Predicted human hepatic or oral clearance (CLhep or CLoral) of erlotinib from primary cultures of human hepatocytes treated with DMSO, efavirenz, or rifampin. *P < 0.05 versus DMSO; nonparametric Friedman analysis of variance followed by Dunn’s multiple comparison test.

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Predicted human hepatic or oral clearance (CLhep or CLoral) of erlotinib from primary cultures of human hepatocytes treated with DMSO, efavirenz, or rifampin. *P < 0.05 versus DMSO; nonparametric Friedman analysis of variance followed by Dunn’s multiple comparison test.

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Comparison

The parameters used for the prediction of hepatic clearance and the comparisons of observed and predicted CL oral values for erlotinib with prediction errors Observed CL oral values (1.9, 3.3, 1.1, 5.3, 5.75, 4.08) were obtained from literature ( N = 6) ( Messersmith et al., 2004 ; Miller et al., 2007 ; Rudin et al., 2008 ; van Erp et al., 2009 ; Padda et al., 2012 ). Predicted CL oral values (0.853, 0.696, 0.997, 0.793, 0.651, 0.668) were obtained from six different vehicle-treated human hepatocytes.

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: The parameters used for the prediction of hepatic clearance and the comparisons of observed and predicted CL oral values for erlotinib with prediction errors Observed CL oral values (1.9, 3.3, 1.1, 5.3, 5.75, 4.08) were obtained from literature ( N = 6) ( Messersmith et al., 2004 ; Miller et al., 2007 ; Rudin et al., 2008 ; van Erp et al., 2009 ; Padda et al., 2012 ). Predicted CL oral values (0.853, 0.696, 0.997, 0.793, 0.651, 0.668) were obtained from six different vehicle-treated human hepatocytes.

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques:

Recovery of ritonavir-mediated inhibition (top) and efavirenz-mediated induction (bottom) of erlotinib metabolism in primary cultures of human hepatocytes. Data are representative of three individual experiments each performed in duplicate. Error bars represent standard deviation.

Journal: Drug Metabolism and Disposition

Article Title: Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer

doi: 10.1124/dmd.113.052100

Figure Lengend Snippet: Recovery of ritonavir-mediated inhibition (top) and efavirenz-mediated induction (bottom) of erlotinib metabolism in primary cultures of human hepatocytes. Data are representative of three individual experiments each performed in duplicate. Error bars represent standard deviation.

Article Snippet: Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. (2008) The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Techniques: Inhibition, Standard Deviation